Prostin VR Pediatric inj.

Prostin VR Pediatric Drug Description Prostin VR Pediatric® (alprostadil) Injection, USP 500 micrograms per mL WARNING Apnea is experienced by about 10 to 12% of neonates with congenital heart defects treated with PROSTIN VR PEDIATRIC Sterile Solution. Apnea is most often seen in neonates weighing less than 2 kg at birth and usually appears during the first hour of drug infusion. Therefore, respiratory status should be monitored throughout treatment, and PROSTIN VR PEDIATRIC should be used where ventilatory assistance is immediately available. DRUG DESCRIPTION PROSTIN VR PEDIATRIC Sterile Solution for intravascular infusion contains 500 micrograms alprostadil, more commonly known as prostaglandin E1, in 1.0 ml dehydrated alcohol. The chemical name for alprostadil is (11α, 13E, 15S)-11, 15 dihydroxy -9- oxoprost-13-en-1-oic acid, and the molecular weight is 354.49. Alprostadil is a white to off-white crystalline powder with a melting point between 110° and 116° C. Its sol...